Giuliano da Sangallo held several positions as military and hydraulic engineer. His technical interests are documented in his manuscript in the Vatican Library and in his Sienese notebook. These manuscripts, which he began in 1465, depict a variety of machines, many of them taken from the works of Francesco di Giorgio. The most notable are devices for moving obelisks and even a pyramid.
Giuliano's nephew, Antonio da Sangallo the Younger, was a successful engineer as well. He undoubtedly had access to the manuscripts of the Sienese engineers: one set of his drawings shows machines derived from Francesco di Giorgio and Taccola.