The Museum, opened in 1990, forms part of the Siena Museum System. It is located in the Town Hall of Cetona, a building dating from the second half of the 16th century. The objects, coming from the Cetona massif, document the various stages of population of the area, from the Middle Palaeolothic to the Bronze Age. Informative panels and dioramas illustrate prehistoric cultural evolution, with special attention to the village of Santa Maria in Belverde, highly significant for an understanding of the Bronze Age. Objects of ancient craftsmanship are displayed along with an environmental reconstruction enriched by findings from archaeologicial excavations in the surrounding areas.

In the vicinity of the museum is the Belverde Archaeological-Naturalist Park, established to safeguard and promote the sites in the area. Guided tours bring visitors into contact with the prehistoric villages in the Cetona area, surrounded by magnificent natural scenery.