Son of Giuseppe Gualdo, he was born in Vicenza on July 25, 1553, studied law in Padua and graduated there in utroque iure on May 10, 1581. From November 29, 1579 he had become a man of the cloth, and in 1585 was ordained a priest in Vicenza and shortly afterwards was made a canon. But he had already gone to Rome in 1582, highly recommended by Cardinal Castagna who, being made Pope Urban VII, called him to manage the office of Secretary of Petitions. At the Pope’s death he returned to Vicenza and, having given up his canonship in 1591, established himself in Padua, however making frequent trips to Rome, where he sojourned for long periods. In 1596 he was called by the Bishop of Padua, Marco Cornaro, to be elected as his Vicar General and, on November 12, 1609, as head priest of the Cathedral. He wrote a biography of Giovanni Vincenzio Pinelli, who had been his close friend and with whose Neapolitan relatives he had maintained close ties. We also know that he had "a great knack for composing verses in the rustic Paduan dialect". He died in Padua on October 16, 1621.

The Works of Galileo Galilei, national edition edited by Antonio Favaro, Florence, Barbčra, 1899-1909, vol. XX, Biographical Index, to v.